I've ready Asylum, and really liked it. I meant to get Shadow Puppets, just never quite got around to it. And I think you're right, Spike does know, at least that Angel's not a vampire, because he's usually wouldn't be helping Angel out of a fight that way.

As for Spike and Connor, like I said, I hope Spike doesn't know, just because I want to see the scene where he finds out, but he probably does.